13 min read | Published September 16, 2025 | by Erica S.
Central Mexico's Bajío region has quietly become one of the most compelling destinations for international buyers seeking quality of life without the premium price tag. Unlike Mexico's crowded coastal resort towns, the Bajío offers something rarer: authentic colonial cities with modern infrastructure, established expat communities alongside colorful local culture, and healthcare standards that rival major metropolitan areas—all at costs that make financial sense. Whether you're planning retirement, seeking a family-friendly relocation, or exploring remote work possibilities, these six carefully selected towns represent the best balance of safety, affordability, and livability that Central Mexico has to offer in 2025.
TL:DR - Key Takeaways
At a Glance: Central Mexico's Bajío region consistently ranks among Mexico's safest areas with established expat communities, quality healthcare infrastructure, and diverse housing options. The six featured towns offer different lifestyle experiences while sharing highland climate, cultural richness, and cost advantages over coastal resort areas. Most cities provide direct property ownership for foreigners without fideicomiso requirements, making real estate transactions straightforward for international buyers.
Thinking about swapping your struggles for sunshine, Wonder Bread for warm tortillas, and sticker-shock rent for numbers that compute without inducing a nervous breakdown? Same. If you’re weighing the best towns to live in Mexico 2025, look no further than the Central Highlands, also known as the Bajio, or “the lowlands.” Yes, that’s right: these are highland-lowlands, meaning lush basins and easygoing plains snuggled into a cradle of magnificent mountains.
This region—anchored by San Miguel de Allende, Querétaro City, Guanajuato City, León, San Luis Potosí, and Dolores Hidalgo—blends colonial charm with modern infrastructure, a reputation for safety, and ridiculously livable costs. In other words: a rare combo of romance and viable metrics.
Below, I’ll break down each city’s relocation vibes with the things that matter most: safety, healthcare access, cost of living, walkability & infrastructure, internet, culture, and real estate. Whether you’re a retiree aiming for low-stress elegance, a family seeking schools and parks, a digital nomad craving bandwidth and good coffee, or an investor scouting affordable communities in Central Mexico, we’ll get you oriented.
Safety & stability. Several Bajío states are consistently rated among Mexico’s more peaceful, with Querétaro often singled out for strong governance and low violent-crime rates relative to national averages. Towns like San Miguel de Allende also maintain high visibility policing in historic cores and tourist corridors.
The Bajío region is home to more than 15 Hospital Ángeles locations, providing world-class medical care at prices up to 70% lower than equivalent U.S. treatments.
Climate & infrastructure. Think highland mild: fewer AC bills, more patio time. You get well-maintained roads, decent public transit in larger cities, and widespread fiber or high-speed internet—translation: Zooming without the doom.
Healthcare. From Hospital Ángeles in Querétaro and León to private clinics in San Luis Potosí (SLP), quality care is easy to reach—often at a fraction of U.S. prices. If “live in Mexico with good healthcare access” is on your checklist, the Bajío checks it.
Background: Picture this: a 16th-century silver mining town that got a second act as an artist colony when the GI Bill sent American art students south in the 1940s. Now it's the poster child for "successful expat town" - UNESCO-protected, Instagram-ready, and home to about 175,000 people (including a sizable crew who definitely know where to get the best breakfast burrito at 10 AM on a Tuesday).
Vibe: Artsy small city, curated colonial mood, big expat energy.
Best for: Creatives, retirees, creative retirees, wellness folks; investors seeking strong short-let demand.
Bottom line: If you want art-soaked, walkable, and warmly social, San Miguel is your A-list pick among the best places to live in Mexico—just budget a tick higher than in smaller or less touristed towns.
Background: The stealth winner. While everyone argues about CDMX versus Guadalajara, Querétaro quietly became Mexico's most livable big city. Population 1.4 million and climbing fast, thanks to aerospace companies, tech firms, and people who figured out you can have your historic cobblestones AND your Costco. Oh, and it's where Mexico's independence was actually planned - they just celebrated the party 45 minutes away in Dolores.
Vibe: Polished, prosperous, quietly cosmopolitan—colonial heart with Costco soul.
Best for: Families, professionals, investors; anyone who wants safety, schools, and a no-drama city.
Bottom line: Querétaro is the stealth “have-it-all” choice—safest cities in Mexico from the US shortlists love it, and day-to-day life is easy mode without Mexico City’s chaos.
Background: Built in a valley so narrow they had to put the roads underground and paint the houses rainbow colors so you could find your way home. About 194,000 people call this university town home, plus whatever number of students are currently debating Cervantes in the tunnels. Silver made it rich in the 1600s; culture keeps it relevant today.
Vibe: University-town bohemia; rainbow hills, tunnels, callejones; culture on tap.
Best for: Budget-savvy romantics, active retirees, Spanish-learning culture nerds, writers.
Bottom line: If your soul craves “Old-World, on foot, with intellectual buzz,” this is your jewel. Among the best towns to live in Mexico 2025 purely for culture-per-peso, Guanajuato City is hard to beat.
Background: Mexico's shoe capital - seriously, if you're wearing leather footwear, there's a decent chance it came from here. This 1.6-million-person metro area figured out how to be proudly Mexican AND globally connected. Less "come for the charm," more "come for the quality of life at prices that don't require selling a kidney."
Vibe: Big city, bold value. Leather capital turned into a modern hub—malls, medical, fútbol, family Sundays.
Best for: Families and professionals who want first-class life at coach prices; long-term buyers.
Bottom line: León is the anti-expat-bubble. If you want “real Mexico” with good healthcare access and giant-city convenience—minus tourist inflation—this is it.
Background: The city that makes other capitals jealous. Population 1.2 million, elevation high enough to skip the sweltering, and close enough to waterfalls that weekend adventure is a given. Founded by silver money in 1592, now running on the kind of steady prosperity that doesn't need to brag about itself.
Vibe: Calm capital with a “little CDMX” grid, Tangamanga Park as your backyard, and weekend waterfall road trips.
Best for: Wellness-minded retirees, families who want space and safety, nature lovers.
Bottom line: A balanced, affordable community in Central Mexico where daily life is low-stress and outdoorsy. If the words “sanctuary city” speak to you, put SLP on your scouting list.
Background: Population 148,000, but feels smaller because everyone knows the ice cream guy. This is where Mexican independence started in 1810 - Father Hidalgo rang the bell, and the rest is history. These days it's famous for ceramics, surprisingly good wine, and being close enough to San Miguel's action without San Miguel's prices.
Vibe: Small-town history with pottery, vineyards, and children kicking footballs across the plaza at dusk.
Best for: Independent retirees and remote workers craving authentic, super-budget living—plus proximity to San Miguel without San Miguel prices.
Bottom line: Dolores is the “live local, breathe easy” option: affordable, authentic, and after three scoops you realize you’ve made friends with the ice cream guy. Plan for trips to bigger cities for medical and bigger nights out.
As always: know your neighborhood, keep normal city awareness, and make friends with your local pharmacy doctor. For anything major, you’re within an hour or two of a Hospital Ángeles or equivalent. That “live in Mexico with good healthcare access” goal? Check.
Will Zoom freeze? Short answer: not if you pick smart. Querétaro, León, and SLP are fiber-rich; San Miguel and Guanajuato City have solid coverage with expanding fiber zones. Before signing a lease, speed-test at the property and ask neighbors which provider actually shows up when it rains.
Pro move: Work with bilingual, locally reputable agents, and always hire an independent notario and attorney. Title due diligence is not optional; it’s the whole game.
Remember: the “best place to live in Mexico” is personal. The right town is the one where your heart feels at home.